Progress Reports Session Antibodies Anti-DFS70

31 de May de 2017

Last session of the program of lectures Valdecilla Progress Reports 2016-2017 will take place on the 7th of May. The conference will be given by Juan Irure Ventura, 4th year medical student in the Immunology Service of the HUMV. Graduated in Biochemistry by the Faculty of Sciences of the University of Navarra (2009-2013). Author of six international publications, as well as more than 20 papers presented at national and international congresses.

The session will be about “Anti-DFS70 antibodies, a new biomarker that can discriminate ana-associated autoimmune rheumatic disease (AARD) from non- AARD patients. A cost-effectiveness study” and is briefly summarized below:

The presence of antinuclear antibodies (ANA) is associated with a wide range of ANA-associated autoimmune rheumatic diseases (AARD). The most commonly method used for the detection of ANA is indirect immunofluorescence (IIF) on HEp-2 cells. This method is very sensitive but unspecific. As a consequence, ANA testing on HEp-2 substrates outside a proper clinical specialist framework may lead to inappropriate referrals to tertiary care specialists and, worst case inappropriate and potentially toxic therapy for the patient. Among ANA, isolated anti-DFS70 antibodies represent a potentially important biomarker that can be clinically used to discriminate AARD from non-AARD patients in ANA IIF positive individuals. Therefore, their presence may avoid unnecessary follow-up testing and referrals. The implementation of a new ANA workup algorithm allowing for the identification of anti-DFS70 antibodies is cost-effective through the reduction of both unnecessary follow-up testing and outpatient clinic visits generated by the clinical suspicion of a potential AARD.

This program of seminars is given by young researchers on the field of IDIVAL’s clinic and laboratories. Speakers will explain the scientific advances of their current research projects. With the idea of debating and networking, the main goal of these meetings, all the predoctoral contracts, Post-MIR Valdecilla López Albo researchers, Río Hortega and Inn-Val grants are invited to attend to these sessions as part of their training. 

The meeting will take place on the 7th of June in lecture room 4-5, pavilion 16 of the HUMV (1st floor) and has a capacity of 30 people. The session will be given in English and will last around 30 minutes and follow by a debate.

Researchers who attend 80% of the meetings throughout the academic year will receive a certificate of assistance.

For any questions regarding Progress Reports sessions, please contact the department at