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Neomycin resistance gene confers resistance to the nucleoside analog fludarabine

18 de April de 2017

The Laboratory of Molecular Hematology, led by IDIVAL researcher Carlos Pipaón, has found while working with G418-resistant stably transfected cells, they realized the neomycin resistance gene (NeoR), which encodes the aminoglycoside-3′-phosphotransferase-IIa [APH(3′)-IIa], also confers resistance to the nucleoside analog fludarabine. Fludarabine is a cytostatic drug widely used in the treatment of hematologic and solid tumors […]

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Valdecilla brand exceeds 100000 references in international literature

10 de April de 2017

Valdecilla brand, created in 1929, has been cited more than 100,000 times by the international biomedical literature, according to data obtained on the Web of Science database. According to these data, papers published by the authors who have in their affiliation the brand Valdecilla (exclusive brand worldwide of our Hospital) have been referenced in more […]

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Intermediate CharcotMarieTooth disease

Charcot-Marie-Tooth disease (CMT) is the most common hereditary neuropathy that, according to the values of motor conduction velocity (MCV) of the median nerve (normal, ≥49 m / s), is divided into three basic patterns: i / demyelinating, CMT1 with MCV 38 / m / s (average around 45 m / s); And iii / intermediate, […]

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IDIVAL publishes the advance of the 2016 report

1 de April de 2017

IDIVAL has just published the progress of its annual report summarizing the main milestones and data of activity developed, both in terms of scientific production and economic results. Throughout its 22 pages prologued by the President of the IDIVAL Board of Trustees and Counselor of Health of the Government of Cantabria, Maria Luisa Real, the […]

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Myeloid Dendritic Supressor Cells in the monitoring of renal transplantation

17 de March de 2017

Institute of Health Carlos III (ISCIII) has granted the research lines of Transplantation and Autoimmunity group at the Health Research and Development Strategy 2016. This group is part of the Health Research Institute Marques de Valdecilla (IDIVAL) and is leaded by the researcher Marcos López Hoyos, Head of the Immunology Department at the HUMV (Marques […]

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CIBER incorporates IDIVALs group of infection and immunity of the digestive system

5 de March de 2017

Group of Infection and Immunity of the Digestive System of IDIVAL led by from Marqués de Valdecilla University Hospital and the University of Cantabria has just joined as a Group linked to CIBER. This Group focuses on the study of viral hepatitis where it has already become a national reference, and in liver fat deposition […]

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Validation of schizophrenia gene expression profile in a preclinical model of maternal infection during pregnancy

20 de February de 2017

Animal models of schizophrenia constitute at this moment fundamental experimentation tools to further explore on the etiological basis of this pathology, leading to the discovery of new biological targets and innovative therapeutic strategies for its treatment. Our research group Prof. Dr. Crespo-Facorro, Dr. Juan F. Lopez-Giménez (CSIC) and the research team of Prof. Dr. Gonzalez-Maeso […]

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Targeted sequencing for the molecular diagnosis of diffuse large cell lymphoma B

15 de February de 2017

Institute of Health Carlos III granted the project “Targeted exonic next generation sequencing for the molecular diagnosis and cell free tumor DNA analysis as screening method for patients with DLBCL” in the call for grants Health Research and Development Strategy 2016 File Nº: PI16/01397 with the amount of 98.615€. The research project is led by Dr. Santiago […]

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Valdecilla in the editorial of the journal Science

6 de February de 2017

This week the journal Science has published in the editorial a paper in which have collaborated researchers from the University Hospital Marqués de Valdecilla and the University of Cantabria. The work has also been referenced in BioCentury. This reference marks a real milestone and points out the enormous interest and projection of the discoveries that […]

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Mechanisms of Antimicrobial Resistance and Host-Pathogen Interactions

31 de January de 2017

Our ability to control infectious diseases is continuously being eroded by antimicrobial resistance, a current major health problem worldwide. A large proportion of the research activities in our group is related to the study of physiological and biochemical aspects of the mechanisms of resistance to antimicrobial agents in bacteria. We consider clinical relevant Enterobacteria and […]

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